Cancer is the predominant medical condition behind death worldwide. It is a multi-stage disease that arises from the unrestricted development of abnormal cells. Cancer begins with genetic changes and grows almost anywhere in the body. Inherited genetic mutation contributes to a minor ratio of cancer. Most of the cancer cases are a result of carcinogens or cancer-inducing chemicals acquired through lifestyle. Roman numerals 0 to IV indicates cancer stages. Thus, it more or less predicts the chances of recovery. Population-based health studies suggest that naturally occurring phytochemicals tend to be promising in cancer therapy. Phytochemicals are plant substances that may help fight cancer and heart diseases to an extent. It is also called phytonutrients. There are about 4,000 different varieties of phytochemicals with distinct health benefits. Eating a varied diet of colorful plant foods adds required phytochemicals to the diet. Dietary phytochemicals get incorporated in cancer treatment plans due to their availability, safety, and low toxicity. It can also disrupt cancer-causing aberrant signaling pathways. Boniol, for example, is an alkyl catechol phytochemical with antiproliferative activity on prostate cancer. Unfortunately, there are some phytochemicals with potential carcinogens or tumor promoters despite being actively used in cancer therapy.
Phytochemicals impart the aroma, taste, and color of plant-derived foods. Eating phytochemical-rich foods reduces the risk of relapse after cancer treatments. The distinct and beneficial types of phytochemicals include:
Phenolic compounds or polyphenols represent the largest category of phytochemicals.
It includes flavonoids, phenolic acids, and non-flavonoid polyphenols. Around 45% of plant products are rich in polyphenols.
It is anti-cancerous, vasodilating, and antimicrobial.
Apples, citrus fruits, coffee, berries, green tea, and wine are sources of polyphenols.
Terpenoids phytochemical is a detoxifying agent.
It consists of carotenoid terpenoids and non-carotenoid terpenoids. Antimicrobial, antirheumatics, and hepatic dal roles get exhibited by terpenoids.
Sweet potato, pumpkin, and carrots are rich in all carotene forms. However, ursolic acid, phytosterols, limonene, saponins, ginkgolide, and perillyl alcohol are non-carotenoid terpenoids.
They can be available through chickpeas, cherries, vegetable oil, oregano, peppermint, and apples.
The occurrence of terpenoids is 27% in natural products. Zeaxanthin, lutein, lycopene, and beta-carotene are all types of carotenoids.
They support vision, improve immunity, and boost skin regeneration.
Non-sulfur-containing indoles, allylic sulfides, and glucosinolates are the subcategories of thiols.
People with a thiol-rich diet exhibited a decrease in cancer-related hormones.
In addition, glucosinolates can bring down the rate of tumor growth. Brussels sprouts, cabbage, garlic, leeks, and other cruciferous vegetables provide thiols.
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